Description
Product Characteristics:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
Synonyms: Serine Palmitoyltransferase, SPTLC-2, LCB 2, LCB2, LCB2a, Long chain base biosynthesis protein 2, Long chain base biosynthesis protein 2a, Serine palmitoyl CoA transferase 2, Serine palmitoyltransferase 2, Serine palmitoyltransferase long chain base subunit 2, Serine palmitoyltransferase subunit II, Serine-palmitoyl-CoA transferase 2, SPT 2, SPT2, SPTC2_HUMAN, SPTLC 2, Sptlc2.
Target Information: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]